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12(S)-HETE
🥰Excellent
Catalog No. T37047Cas No. 54397-83-0
Alias 12S-HETE
12(S)-HETE, a 12-lipoxygenase metabolite of arachidonic acid, is mitogenic for cancer cell proliferation and enhances angiotensin II-induced contraction of BLT2 (type 2 receptor in arteries of leukotriene B4 mice) and TP (thromboxane receptor)-mediated mechanisms. 12(S)-HETE promotes superoxide and isothromboxane-like metabolites in arterial endothelial cells. production.
12(S)-HETE
🥰Excellent
Catalog No. T37047Alias 12S-HETECas No. 54397-83-0
12(S)-HETE, a 12-lipoxygenase metabolite of arachidonic acid, is mitogenic for cancer cell proliferation and enhances angiotensin II-induced contraction of BLT2 (type 2 receptor in arteries of leukotriene B4 mice) and TP (thromboxane receptor)-mediated mechanisms. 12(S)-HETE promotes superoxide and isothromboxane-like metabolites in arterial endothelial cells. production.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 μg | $443 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 12(S)-HETE, a 12-lipoxygenase metabolite of arachidonic acid, is mitogenic for cancer cell proliferation and enhances angiotensin II-induced contraction of BLT2 (type 2 receptor in arteries of leukotriene B4 mice) and TP (thromboxane receptor)-mediated mechanisms. 12(S)-HETE promotes superoxide and isothromboxane-like metabolites in arterial endothelial cells. production. |
| Alias | 12S-HETE |
| Molecular Weight | 320.47 |
| Formula | C20H32O3 |
| Cas No. | 54397-83-0 |
| Smiles | C(\[C@H](C/C=C\CCCCC)O)=C/C=C\C/C=C\CCCC(O)=O |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
| Solubility Information | PBS(pH 7.2): < 0.1 mg/mL (insoluble) 0.1 M Na2CO3: 1 mg/mL (3.12 mM), Sonication is recommended. PBS (pH 7.2): 0.8 mg/mL <0.1 M Na2CO3: 2 mg/mL Ethanol: 1 mg/mL (3.12 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
0.1 M Na2CO3/Ethanol
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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