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12R-LOX-IN-2

🥰Excellent
Catalog No. T77677Cas No. 3026677-37-9

12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.12R-LOX-IN-2 also decreases the protein level of Ki67 and the mRNA expression of IL-17A in IMQ-induced cells. 12R-LOX-IN-2 may be useful in the study of psoriasis and other skin-associated inflammatory diseases.

12R-LOX-IN-2

12R-LOX-IN-2

🥰Excellent
Purity: 99.84%
Catalog No. T77677Cas No. 3026677-37-9
12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.12R-LOX-IN-2 also decreases the protein level of Ki67 and the mRNA expression of IL-17A in IMQ-induced cells. 12R-LOX-IN-2 may be useful in the study of psoriasis and other skin-associated inflammatory diseases.
Pack SizePriceAvailabilityQuantity
5 mg$40In Stock
10 mg$64In Stock
25 mg$129In Stock
50 mg$198In Stock
100 mg$328In Stock
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Purity:99.84%
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Product Introduction

Bioactivity
Description
12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.12R-LOX-IN-2 also decreases the protein level of Ki67 and the mRNA expression of IL-17A in IMQ-induced cells. 12R-LOX-IN-2 may be useful in the study of psoriasis and other skin-associated inflammatory diseases.
Chemical Properties
Molecular Weight271.31
FormulaC19H13NO
Cas No.3026677-37-9
SmilesOC=1C=CC(C2=NC=3C=CC=CC3C=C2)=C4C=CC=CC14
Storage & Solubility Information
Storagestore at low temperature | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (184.29 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6858 mL18.4291 mL36.8582 mL184.2910 mL
5 mM0.7372 mL3.6858 mL7.3716 mL36.8582 mL
10 mM0.3686 mL1.8429 mL3.6858 mL18.4291 mL
20 mM0.1843 mL0.9215 mL1.8429 mL9.2146 mL
50 mM0.0737 mL0.3686 mL0.7372 mL3.6858 mL
100 mM0.0369 mL0.1843 mL0.3686 mL1.8429 mL

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