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5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole

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Catalog No. T9858Cas No. 2863687-18-5

Antileishmanial agent-2 is a 3-Br-isoxazoline-Based Inhibitors against Plasmodium falciparum (D10 and W2 strains) and Leishmania spp. (L. infantum and L. tropica) Promastigotes with IC50s of 0.035, 0.058, 3.5 and 7.5 μM.

5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole

5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole

🥰Excellent
Purity: 99.58%
Catalog No. T9858Cas No. 2863687-18-5
Antileishmanial agent-2 is a 3-Br-isoxazoline-Based Inhibitors against Plasmodium falciparum (D10 and W2 strains) and Leishmania spp. (L. infantum and L. tropica) Promastigotes with IC50s of 0.035, 0.058, 3.5 and 7.5 μM.
Pack SizePriceAvailabilityQuantity
1 mg$70In Stock
5 mg$157In Stock
10 mg$232In Stock
25 mg$355In Stock
50 mg$497In Stock
100 mg$666In Stock
200 mg$898In Stock
1 mL x 10 mM (in DMSO)$163In Stock
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Purity:99.58%
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Product Introduction

Bioactivity
Description
Antileishmanial agent-2 is a 3-Br-isoxazoline-Based Inhibitors against Plasmodium falciparum (D10 and W2 strains) and Leishmania spp. (L. infantum and L. tropica) Promastigotes with IC50s of 0.035, 0.058, 3.5 and 7.5 μM.
Targets&IC50
P. falciparum:35 nM(D10 strains), P. falciparum:58 nM(W2 strains)
Chemical Properties
Molecular Weight350.21
FormulaC15H16BrN3O2
Cas No.2863687-18-5
SmilesC(C)(C)(C)C1=CC=C(C=2N=C(ON2)C3ONC(Br)=C3)C=C1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 65 mg/mL (185.6 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8554 mL14.2771 mL28.5543 mL142.7715 mL
5 mM0.5711 mL2.8554 mL5.7109 mL28.5543 mL
10 mM0.2855 mL1.4277 mL2.8554 mL14.2771 mL
20 mM0.1428 mL0.7139 mL1.4277 mL7.1386 mL
50 mM0.0571 mL0.2855 mL0.5711 mL2.8554 mL
100 mM0.0286 mL0.1428 mL0.2855 mL1.4277 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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