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5-hydroxytryptophan (NSC-92523) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 mg | 47 € | In Stock | |
1 mL x 10 mM (in DMSO) | 47 € | In Stock |
Description | 5-hydroxytryptophan (NSC-92523) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant. |
In vitro | 5-Hydroxytryptophan exhibits toxicity in mice with an LD50 of 1800 mg/kg. In rats, it demonstrates effects at a dosage of 300 mg/kg when administered intragastrically (i.g.). |
In vivo | 5-Hydroxytryptophan is an intermediate in the biosynthesis of serotonin from the essential amino acid L-tryptophan, which can easily cross the blood-brain barrier and effectively increase the synthesis of serotonin within the central nervous system. It has been shown to improve conditions such as depression, chronic headaches, and insomnia. |
Alias | NSC-92523 |
Molecular Weight | 220.22 |
Formula | C11H12N2O3 |
Cas No. | 56-69-9 |
Smiles | NC(CC1=CNC2=CC=C(O)C=C12)C(O)=O |
Relative Density. | 1.484 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 60 mg/mL (272.44 mM) ![]() Ethanol: < 1 mg/mL (insoluble or slightly soluble) H2O: 4 mg/mL (18.16 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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