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Product Introduction

Bioactivity

Description	6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Alias	Epsilon-Amino-n-caproic Acid, EACA, 6-Aminohexanoic acid, (6-)ε-Aminocaproic acid

Chemical Properties

Molecular Weight	131.17
Formula	C₆H₁₃NO₂
Cas No.	60-32-2
Smiles	NCCCCCC(O)=O
Relative Density.	1.042 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 24 mg/mL (183 mM)

Ethanol: 1 mg/mL (7.62 mM)

DMSO: < 1 mg/mL (insoluble）

Solution Preparation Table

Ethanol/H2O

	1mg	5mg	10mg	50mg
1 mM	7.6237 mL	38.1185 mL	76.2369 mL	381.1847 mL
5 mM	1.5247 mL	7.6237 mL	15.2474 mL	76.2369 mL

H2O

	1mg	5mg	10mg	50mg
10 mM	0.7624 mL	3.8118 mL	7.6237 mL	38.1185 mL
20 mM	0.3812 mL	1.9059 mL	3.8118 mL	19.0592 mL
50 mM	0.1525 mL	0.7624 mL	1.5247 mL	7.6237 mL
100 mM	0.0762 mL	0.3812 mL	0.7624 mL	3.8118 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

plasminogenplasminlysisInhibitorinhibitfibrinolysisclotbleedingantifibrinolytic6-Aminocaproic acid6Aminocaproic acid6 Aminocaproic acid(6-)ε-Aminocaproic acid