Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

A-286982

Catalog No. T21781Cas No. 280749-17-9

A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1.

A-286982

A-286982

Purity: 97.81%
Catalog No. T21781Cas No. 280749-17-9
A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
2 mg$43In Stock
5 mg$68In Stock
10 mg$109In Stock
25 mg$222In Stock
50 mg$369In Stock
100 mg$549In Stock
1 mL x 10 mM (in DMSO)$74In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "A-286982"

Select Batch
Purity:97.81%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1.
Targets&IC50
LFA1:44 nM, ICAM1:35 nM
In vitro
A 286982 is a selective inhibitor of LFA-1/ICAM-1 binding and LFA-1 with IC50 values of 44 nM and 35 nM, respectively[2].
Chemical Properties
Molecular Weight453.55
FormulaC24H27N3O4S
Cas No.280749-17-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45.35 mg/mL (100 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2048 mL11.0241 mL22.0483 mL110.2414 mL
5 mM0.4410 mL2.2048 mL4.4097 mL22.0483 mL
10 mM0.2205 mL1.1024 mL2.2048 mL11.0241 mL
20 mM0.1102 mL0.5512 mL1.1024 mL5.5121 mL
50 mM0.0441 mL0.2205 mL0.4410 mL2.2048 mL
100 mM0.0220 mL0.1102 mL0.2205 mL1.1024 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy A-286982 | purchase A-286982 | A-286982 cost | order A-286982 | A-286982 chemical structure | A-286982 in vitro | A-286982 formula | A-286982 molecular weight