Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AC-262536 is a selective androgen receptor (SAR) modulator and exhibits potent agonist activity at the androgen receptor. It has partial agonist activity with respect to testosterone and suppresses luteinizing hormone.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 39.00 | |
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 113.00 | |
25 mg | In stock | $ 247.00 | |
50 mg | In stock | $ 422.00 | |
100 mg | In stock | $ 628.00 | |
500 mg | In stock | $ 1,350.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | AC-262536 is a selective androgen receptor (SAR) modulator and exhibits potent agonist activity at the androgen receptor. It has partial agonist activity with respect to testosterone and suppresses luteinizing hormone. |
In vitro | AC-262536 inhibits dihydroxytestosterone (DHT)-induced proliferation of LNCaP in a dose-dependent manner. The effects are significant with 100 nM, and reaches a plateau with 1 μM[2]. |
In vivo | In male sprague-dawley rats, administration of AC-262536 (subcutaneous injection, once daily for 14 consecutive days) significantly decreased LH levels by about 40% at the 3 mg/kg dose. At the 10 and 30 mg/kg doses, the effects of AC-262536 were significantly stronger than Testosterone Propionate (TP) : 1.91±0.32 ng/mL and 1.53±0.34 ng/mL vs. 3.12±0.69 ng/mL, respectively[2]. |
Synonyms | AC262536 |
Molecular Weight | 278.35 |
Formula | C18H18N2O |
CAS No. | 870888-46-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (179.63 mM)
You can also refer to dose conversion for different animals. More
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AC-262536 870888-46-3 Endocrinology/Hormones Androgen Receptor SARM AC 262536 modulator Inhibitor receptor AC262536 androgen anabolic inhibit non-steroidal inhibitor