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Aristolochic acid B

Catalog No. T7031 CAS 475-80-9

Synonyms: Aristolochic Acid II

Aristolochic acid B is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo, Aristolochic acid B shows more carcinogenic risk than aristolochic acid I, and this may be, at least partly, the result of its increased levels in kidney and plasma.

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Aristolochic acid B, CAS 475-80-9

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Aristolochic Acid II
Molecular Weight	311.25
Formula	C16H9NO6
CAS No.	475-80-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mg/mL (32.13 mM)

Chloroform: Soluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Tian M, et al. Production, characterization of a monoclonal antibody against aristolochic acid-II and development of its assay system.[J]. Am J Chin Med, 2008, 36(02):425-436.

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Aristolochic acid B 475-80-9 DNA Damage/DNA Repair DNA inhibit Inhibitor Aristolochic Acid II inhibitor

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