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Chromium picolinate

🥰Excellent
Catalog No. T4575Cas No. 14639-25-9

Chromium picolinate causes DNA damage and mutation. It is an activator of p38.

Chromium picolinate

Chromium picolinate

🥰Excellent
Purity: 98.22%
Catalog No. T4575Cas No. 14639-25-9
Chromium picolinate causes DNA damage and mutation. It is an activator of p38.
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100 mg$41In Stock
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Purity:98.22%
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Product Introduction

Bioactivity
Description
Chromium picolinate causes DNA damage and mutation. It is an activator of p38.
In vivo
Acrivastine (usually 8mg three times daily) is an effective and well-tolerated antihistamine in the treatment of chronic urticaria and allergic rhinitis. Acrivastine causes less drowsiness than clemastine, the incidence of adverse effects being indistinguishable from that with placebo or terfenadine. In the treatment of dermatoses in which histamine has a pathogenetic role, the efficacy of acrivastine is superior to that of placebo and similar to that of usual dosages of clemastine, hydroxyzine, chlorpheniramine, cyproheptadine or terfenadine [1]. Both 4 mg and 8 mg acrivastine alleviate the symptoms of seasonal allergic rhinitis with significant improvements in the symptom scores for sneezing, running nose and the calculated overall score. In addition, 8 mg acrivastine reduces the symptom scores for watery eyes and itchy throat. Acrivastine is both well tolerated and effective in the treatment of seasonal allergic rhinitis [2].
Chemical Properties
Molecular Weight418.3
FormulaC18H12CrN3O6
Cas No.14639-25-9
SmilesO=C1[O-][Cr+3]23([N]=4C(C(=O)[O-]2)=CC=CC4)([N]=5C(C(=O)[O-]3)=CC=CC5)[N]=6C1=CC=CC6
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.18 mg/mL (10 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3906 mL11.9531 mL23.9063 mL119.5314 mL
5 mM0.4781 mL2.3906 mL4.7813 mL23.9063 mL
10 mM0.2391 mL1.1953 mL2.3906 mL11.9531 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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