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Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM)
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | 36 € | In Stock | |
10 mg | 56 € | In Stock | |
25 mg | 107 € | In Stock | |
50 mg | 169 € | In Stock | |
100 mg | 264 € | In Stock | |
200 mg | 372 € | In Stock | |
1 mL x 10 mM (in DMSO) | 40 € | In Stock |
Description | Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either starvation with IC50 of 0.27 μM, and inhibits mTORC1 (Rapamycin; IC50:0.14 μM) |
Targets&IC50 | Autophagy:0.27 μM |
Alias | tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate |
Molecular Weight | 417.52 |
Formula | C21H27N3O4S |
Cas No. | 2375541-45-8 |
Smiles | CC(C)Oc1ccc(cc1)C(=O)Nc1nc2CCN(Cc2s1)C(=O)OC(C)(C)C |
Relative Density. | 1.252 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 83.33 mg/mL (199.58 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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