Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

BU 224 hydrochloride

Catalog No. T22051Cas No. 205437-64-5

BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.

BU 224 hydrochloride

BU 224 hydrochloride

Purity: 99.2%
Catalog No. T22051Cas No. 205437-64-5
BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.
Pack SizePriceAvailabilityQuantity
2 mg$29In Stock
5 mg$48In Stock
10 mg$73In Stock
25 mg$158In Stock
50 mg$253In Stock
100 mg$367In Stock
200 mg$515In Stock
1 mL x 10 mM (in DMSO)$47In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "BU 224 hydrochloride"

Select Batch
Purity:99.2%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.
In vivo
BU 224 hydrochloride (5 mg/kg; i.p.) attenuated spatial and perirhinal cortex-dependent recognition memory deficits in 5XFAD mice. Fear-conditioning testing revealed that BU 224 hydrochloride also improved both associative learning and hippocampal- and amygdala-dependent memory in transgenic but not in WT mice. In the brain, BU 224 hydrochloride reduced levels of the microglial marker Iba1 and pro-inflammatory cytokines IL-1β and TNF-α and increased the expression of astrocytic marker GFAP in 5XFAD mice[1].
Chemical Properties
Molecular Weight233.7
FormulaC12H12ClN3
Cas No.205437-64-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 3 mg/mL (12.84 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.2790 mL21.3950 mL42.7899 mL213.9495 mL
5 mM0.8558 mL4.2790 mL8.5580 mL42.7899 mL
10 mM0.4279 mL2.1395 mL4.2790 mL21.3950 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy BU 224 hydrochloride | purchase BU 224 hydrochloride | BU 224 hydrochloride cost | order BU 224 hydrochloride | BU 224 hydrochloride chemical structure | BU 224 hydrochloride in vivo | BU 224 hydrochloride formula | BU 224 hydrochloride molecular weight