Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Belvarafenib is a potent and pan RAF inhibitor with antineoplastic activity. The IC50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 40.00 | |
2 mg | In stock | $ 56.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 172.00 | |
25 mg | In stock | $ 288.00 | |
50 mg | In stock | $ 428.00 | |
100 mg | In stock | $ 637.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 98.00 |
Description | Belvarafenib is a potent and pan RAF inhibitor with antineoplastic activity. The IC50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively. |
Targets&IC50 | B-RafV600E:7 nM, B-Raf:56 nM, C-Raf:5 nM |
In vitro | Belvarafenib ?is a potent and pan RAF inhibitor with antineoplastic activity.?The IC50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively.?It also shows high inhibitory activity for FMS, DDR1 and DDR2 kinases, with IC50s of 10 nM, 23 nM and 44 nM, respectively. |
Molecular Weight | 478.93 |
Formula | C23H16ClFN6OS |
CAS No. | 1446113-23-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (52.2 mM)
You can also refer to dose conversion for different animals. More
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Belvarafenib 1446113-23-0 MAPK Raf RG-6185 inhibit GDC-5573 HM 95573 GDC 5573 Inhibitor RG6185 RG 6185 HM95573 HM-95573 GDC5573 Raf kinases inhibitor