Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CFTR corrector 4 is a potent and orally available transmembrane conductance regulator (CFTR) for cystic fibrosis and is a potent (R,R) type active enantiomer. CFTR corrector 4 increases CFTR levels on the cell surface and is a potential compound for the study of cystic fibrosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 68.00 | |
5 mg | In stock | $ 178.00 | |
10 mg | In stock | $ 278.00 | |
25 mg | In stock | $ 563.00 | |
50 mg | In stock | $ 793.00 | |
100 mg | In stock | $ 1,130.00 | |
500 mg | In stock | $ 2,260.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 213.00 |
Description | CFTR corrector 4 is a potent and orally available transmembrane conductance regulator (CFTR) for cystic fibrosis and is a potent (R,R) type active enantiomer. CFTR corrector 4 increases CFTR levels on the cell surface and is a potential compound for the study of cystic fibrosis. |
Targets&IC50 | CFTR:(EC50)130 nM , CFTR:130 nM(EC50) |
In vitro | CFTR corrector 4 (Compound 13) possesses high potency and efficacy with an EC50 of 0.028 μM in HBE-TECC assay that assesses the CFTR function. CFTR corrector 4 is tested its potency and efficacy in human bronchial epithelial (HBE) cells with an EC50 value of 130 nM in the cell surface expression (CSE-HRP) assay.[1] |
Molecular Weight | 539.52 |
Formula | C29H27F2NO7 |
CAS No. | 1918142-34-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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CFTR corrector 4 1918142-34-3 Membrane transporter/Ion channel CFTR inhibitor inhibit