Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

CGP 20712 A

CGP 20712 A
CGP 20712 A (CGP 20712 mesylate) is a selective and potent β1-adrenergic receptor antagonist (IC50: 0.7 nM) with antihypertensive activity, capable of reversing RKT-induced gastric relaxation.
Catalog No. T10778Cas No. 105737-62-0
Select Batch
Purity:99.37%
Contact us for more batch information
Resource Download

CGP 20712 A

Catalog No. T10778Cas No. 105737-62-0
CGP 20712 A (CGP 20712 mesylate) is a selective and potent β1-adrenergic receptor antagonist (IC50: 0.7 nM) with antihypertensive activity, capable of reversing RKT-induced gastric relaxation.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$148In Stock
5 mg$372In Stock
10 mg$548In Stock
25 mg$869In Stock
50 mg$1,170In Stock
100 mg$1,570In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "CGP 20712 A"

Product Introduction

Bioactivity
Description
CGP 20712 A (CGP 20712 mesylate) is a selective and potent β1-adrenergic receptor antagonist (IC50: 0.7 nM) with antihypertensive activity, capable of reversing RKT-induced gastric relaxation.
Targets&IC50
β1-adrenoceptor:0.7 nM, β1-adrenoceptor:0.7 nM
In vitro
In myocyte, saturation experiments conducted in the presence of 300nM CGP 20712A failed to detect specific binding of [125I]-ICYP and [3H]-CGP 12177[2].
In vivo
Pre-treatment with 5mg/kg CGP 20712A (selective β1-adrenoceptor antagonist) in 8-day-old rats did not alter the plasma ACTH response to insulin injection[3].
AliasCGP 20712 mesylate
Chemical Properties
Molecular Weight590.57
FormulaC24H29F3N4O8S
Cas No.105737-62-0
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (135.46 mM), Sonification is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6933 mL8.4664 mL16.9328 mL84.6640 mL
5 mM0.3387 mL1.6933 mL3.3866 mL16.9328 mL
10 mM0.1693 mL0.8466 mL1.6933 mL8.4664 mL
20 mM0.0847 mL0.4233 mL0.8466 mL4.2332 mL
50 mM0.0339 mL0.1693 mL0.3387 mL1.6933 mL
100 mM0.0169 mL0.0847 mL0.1693 mL0.8466 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy CGP 20712 A | purchase CGP 20712 A | CGP 20712 A cost | order CGP 20712 A | CGP 20712 A chemical structure | CGP 20712 A in vivo | CGP 20712 A in vitro | CGP 20712 A formula | CGP 20712 A molecular weight