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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $31 | In Stock | |
2 mg | $45 | In Stock | |
5 mg | $77 | In Stock | |
10 mg | $113 | In Stock | |
25 mg | $263 | In Stock | |
50 mg | $488 | In Stock | |
100 mg | $689 | In Stock | |
1 mL x 10 mM (in DMSO) | $85 | In Stock |
Description | DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine. DMCM showed significant differences in human recombinant GABAA αxβ3γ2 receptor subtypes. For α1, α2, α3, and α5 receptors, their Kis were 10 nM, 13 nM, 7.5 nM, 2.2 nM, respectively. |
In vivo | DMCM has potent convulsant, proconvulsant and anxiogenic properties in vivo. DMCM (20-60 mg/kg; i.p.) produces modest anxiolytic-like effects in γ2I77 mice[2]. |
Molecular Weight | 350.8 |
Formula | C17H19ClN2O4 |
Cas No. | 1215833-62-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | H2O: 22.5 mg/mL (64.1 mM), Sonication is recommended. DMSO: 9 mg/mL (25.7 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
H2O
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