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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $40 | In Stock | |
10 mg | $57 | In Stock | |
25 mg | $72 | In Stock | |
50 mg | $85 | In Stock | |
100 mg | $117 | In Stock | |
500 mg | $238 | In Stock | |
1 mL x 10 mM (in DMSO) | $57 | In Stock |
Description | Dabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively). |
In vitro | In human endothelial cells, Dabrafenib inhibits the release of HMGB1 and down-regulates the HMGB1-dependent inflammatory response by enhancing the expression of cell adhesion molecules (CAM)[1] |
Alias | GSK 2118436B, GSK2118436 Mesylate |
Molecular Weight | 615.67 |
Formula | C24H24F3N5O5S3 |
Cas No. | 1195768-06-9 |
Storage | keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (73.09 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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