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Drospirenone

Catalog No. T1541 CAS 67392-87-4

Synonyms: ZK 3059, Dihydrospirorenone

Drospirenone (ZK 3059) is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.

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Drospirenone, CAS 67392-87-4

Pack Size	Availability	Price/USD
10 mg	In stock	$ 43.00
25 mg	In stock	$ 78.00
50 mg	In stock	$ 133.00
100 mg	In stock	$ 217.00
200 mg	In stock	$ 323.00
500 mg	In stock	$ 543.00
1 mL * 10 mM (in DMSO)	In stock	$ 48.00

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Purity: 100%

Purity: 99.85%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Drospirenone (ZK 3059) is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.

Synonyms	ZK 3059, Dihydrospirorenone
Molecular Weight	366.49
Formula	C24H30O3
CAS No.	67392-87-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 9 mg/mL (24.6 mM)

DMSO: 68 mg/mL (185.5 mM)

H2O: < 1 mg/mL (insoluble or slightly soluble)

References and Literature

1. Bray JD, et al. J Steroid Biochem Mol Biol. 2005 Dec;97(4):328-41.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Anti-Cancer Approved Drug Library EMA Approved Drug Library Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library Anti-Pancreatic Cancer Compound Library Endocrinology-Hormone Compound Library FDA-Approved Drug Library Pediatric Drug Library Immunology/Inflammation Compound Library

Related Products

Related compounds with same targets

Hydrocortisone acetate Fluocinonide Vamorolone GSK9027 Nimodipine Fludrocortisone acetate Prednisolone acetate Desonide

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Drospirenone 67392-87-4 Endocrinology/Hormones Immunology/Inflammation Neuroscience Others Androgen Receptor COX Glucocorticoid Receptor Progesterone Receptor Estrogen/progestogen Receptor ZK 3059 ZK3059 Dihydrospirorenone ZK-3059 inhibit Inhibitor NR3C3 inhibitor

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