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Drospirenone

Catalog No. T1541 CAS 67392-87-4

Synonyms: 屈螺酮, Dihydrospirorenone, ZK 3059

Drospirenone is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.

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Drospirenone, CAS 67392-87-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Drospirenone is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity.

Synonyms	屈螺酮, Dihydrospirorenone, ZK 3059
Molecular Weight	366.501
Formula	C24H30O3
CAS No.	67392-87-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

Ethanol: 9 mg/mL (24.6 mM)

DMSO: 68 mg/mL (185.5 mM)

H2O: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Bray JD, et al. J Steroid Biochem Mol Biol. 2005 Dec;97(4):328-41.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library GPCR Compound Library HIF-1 Signaling Pathway Compound Library Glycometabolism Compound Library Anti-Cancer Metabolism Compound Library Anti-Cardiovascular Disease Compound Library Endocrinology-Hormone Compound Library Inhibitor Library Immunology/Inflammation Compound Library Drug Repurposing Compound Library

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Drospirenone 67392-87-4 免疫与炎症内分泌与激素其他神经科学 Androgen Receptor COX Estrogen/progestogen Receptor Glucocorticoid Receptor Progesterone Receptor Dihydrospirorenone inhibit ZK 3059 Inhibitor NR3C3 inhibitor

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