Powder: -20°C for 3 years | In solvent: -80°C for 1 year
E-7386 is an oral active CBP/ -catenin modulator.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 89.00 | |
5 mg | In stock | $ 269.00 | |
10 mg | In stock | $ 409.00 | |
25 mg | In stock | $ 682.00 | |
50 mg | In stock | $ 969.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 419.00 |
Description | E-7386 is an oral active CBP/ -catenin modulator. |
In vivo | E-7386 is an oral active CBP/ -catenin regulator, which can induce T cells to infiltrate into the tumor in the Wnt1 tumor cogene mouse model and enhance the anti-tumor activity of anti-PD-1 monoclonal antibody.In the Wnt1 model, t-cell infiltration in the vehicle control group was limited, while t-cell infiltration in the E-7386 treatment group was obvious, and E-7386 showed significant anti-tumor activity. |
Synonyms | E7386 |
Molecular Weight | 725.85 |
Formula | C39H48FN9O4 |
CAS No. | 1799824-08-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methanol: 250 mg/mL (344.42 mM), sonification is recommended.
DMSO: 125 mg/mL (172.21 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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E-7386 1799824-08-0 Chromatin/Epigenetic Epigenetic Reader Domain E7386 inhibit Inhibitor E 7386 inhibitor