Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 33.00 | |
5 mg | In stock | $ 52.00 | |
10 mg | In stock | $ 94.00 | |
25 mg | In stock | $ 169.00 | |
50 mg | In stock | $ 285.00 | |
100 mg | In stock | $ 487.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 58.00 |
Description | ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation. |
Targets&IC50 | EPAC2:0.4 μM |
Synonyms | NSC 116966 |
Molecular Weight | 274.38 |
Formula | C16H18O2S |
CAS No. | 5184-64-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 83.33 mg/mL (303.70 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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ESI-05 5184-64-5 GPCR/G Protein cAMP Diacylglycerol acyltransferase diabetes Inhibitor inhibit NSC 116966 Intracranial hemorrhage (ICH) Acyltransferase acyl-CoA:cholesterol acyltransferase insulin secretion mono- acylglycerol acyltransferase NSC-116966 exchange proteins directly activated by cAMP 2 (EPAC2) neurological disorders NSC116966 ESI 05 ESI05 GEF Diglyceride acyltransferase inhibitor