Home Tools

Cart

Elagolix sodium

Catalog No. T5031 CAS 832720-36-2

Synonyms: NBI-56418 sodium, NBI-56418 sodium

Purity 99.93% Datasheet

Elagolix sodium is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively).

Elagolix sodium, CAS 832720-36-2

Pack Size	Availability	Price/USD
2 mg	In stock	48.00
5 mg	In stock	68.00
10 mg	In stock	104.00
25 mg	In stock	227.00
50 mg	In stock	410.00
100 mg	In stock	590.00
1 mL * 10 mM (in DMSO)	In stock	95.00

Bulk Inquiry

Select Batch

Purity 99.93%

HNMR HPLC COA Datasheet MSDS

Biological Description

Chemical Properties

Storage & Solubility Information

Preparing Solutions

Description	Elagolix sodium is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively).
Targets&IC50	GnRHR :ic50 3.7 nM,
In vivo	Elagolix sodium for the treatment of women with moderate to severe endometriosis-associated pain[1]

Synonyms	NBI-56418 sodium , NBI-56418 sodium
Purity	99.93%
Molecular Weight	653.57
Formula	C32H29F5N3NaO5
CAS No.	832720-36-2

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 50 mg/mL (76.50 mM)

H2O: 50 mg/mL (76.50 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Solution 1

Citations

References and Literature

1. Barra F, Scala C, Ferrero S2.Elagolix sodium for the treatment of women with moderate to severe endometriosis-associated pain.Drugs Today (Barc). 2019 Apr;55(4):237-246. 2. Elagolix (Orilissa)--an oral GnRH antagonist for endometriosis pain.[J]. The Medical letter on drugs and therapeutics, 2018.

Related Products

Related compounds with same targets

Degarelix Danazol Relugolix Goserelin acetate Leuprorelin Leuprolide Acetate Elagolix sodium Cetrorelix

Dose Conversion

Safe and effective drug dosing is necessary, regardless of its purpose of administration. Learn More

In vivo Formulation Calculator (Clear solution)

Step One: Enter information below

Dosage

mg/kg

Average weight of animals

Dosing volume per animal

Number of animals

Step Two: Enter the in vivo formulation

% DMSO+

% +

% Tween 80+

% ddH₂O

%DMSO+

Calculate Reset

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

Calculator

Molarity Calculator

Dilution Calculator

Reconstitution Calculation

Molecular Weight Calculator

Mass

Concentration

Volume

Molecular Weight

Molarity Calculator allows you to calculate the

mass of a compound required to prepare a solution of known volume and concentration
volume of solution required to dissolve a compound of known mass to a desired concentration
concentration of a solution resulting from a known mass of compound in a specific volume

See Example

An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

Concentration (Start)

Volume (Start)

Concentration (End)

Volume (End)

Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Calculate the volume of solvent required to reconstitute your vial

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial.
Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Molecule Formula

Molecular Weight g/mol

Enter the chemical formula of a compound to calculate its molar mass and elemental composition

Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

bottom

Tech Support

Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.