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Etarotene
Catalog No. T25393Cas No. 87719-32-2
Alias RO15-1570, RO-15-1570, RO 15-1570, Arotinoid ethyl sulphone
Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a collagenase inhibitor and can be used to study psoriasis.
Etarotene
Catalog No. T25393Alias RO15-1570, RO-15-1570, RO 15-1570, Arotinoid ethyl sulphoneCas No. 87719-32-2
Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a collagenase inhibitor and can be used to study psoriasis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $258 | In Stock | |
| 5 mg | $642 | In Stock | |
| 10 mg | $913 | In Stock | |
| 25 mg | $1,370 | In Stock | |
| 50 mg | $1,850 | In Stock | |
| 100 mg | $2,500 | In Stock | |
| 500 mg | $4,900 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a collagenase inhibitor and can be used to study psoriasis. |
| In vivo | Etarotene (6 mg/kg; oral; 1 and 2 weeks; rats) show weight loss, alopecia, erythema, desquamation of the skin, and alterations of the skeletal system. The present demonstration that the arotinoid ethyl sulfone Etarotene was devoid of bone toxicity constitutes major progress in the pharmacologic development of retinoids with a better balance between therapeutic and adverse effects.[5] |
| Alias | RO15-1570, RO-15-1570, RO 15-1570, Arotinoid ethyl sulphone |
| Molecular Weight | 396.59 |
| Formula | C25H32O2S |
| Cas No. | 87719-32-2 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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