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FSLLRY-NH2 TFA(245329-02-6 free base)

Catalog No. TP1904L CAS TP1904L

FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.

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FSLLRY-NH2 TFA(245329-02-6 free base) Chemical Structure

FSLLRY-NH2 TFA(245329-02-6 free base), CAS TP1904L

Pack Size	Availability	Price/USD
1 mg	In stock	$ 98.00
5 mg	In stock	$ 183.00
10 mg	In stock	$ 277.00
25 mg	In stock	$ 498.00
50 mg	In stock	$ 725.00
100 mg	In stock	$ 987.00
500 mg	In stock	$ 1,980.00

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Purity: 99.32%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	910.99
Formula	C41H61F3N10O10
CAS No.	TP1904L

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mM

References and Literature

1. McLarty et al (2011) Tryptase/protease-activated receptor 2 interactions induce selective mitogen-activated protein kinase signaling and collagen synthesis by cardiac fibroblasts. Hypertension 58 264 PMID: 2. Chen et al (2011) Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in PacT.-induced neuropathic pain. Neuroscience 193 440 PMID: 3. Andoh et al (2012) Involvement of serine protease and proteinase-activated receptor 2 in dermatophyte-associated itch in mice. J.Pharmacol.Exp.Ther. 343 91 PMID:

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Peptide Compound Library Inhibitor Library Bioactive Compounds Library Max NO PAINS Compound Library Bioactive Compound Library

Related Products

Related compounds with same targets

Parmodulin 2 TFLLR-NH2 Protease-Activated Receptor-1, PAR-1 Agonist acetate Vorapaxar VKGILS-NH2 Acetate 2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) ENMD-1068 HCl I-191

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Keywords

FSLLRY-NH2 TFA(245329-02-6 free base) TP1904L GPCR/G Protein Protease-activated Receptor FSLLRY NH2 TFA(245329 02 6 free base) FSLLRY-NH-2 TFA(245329-02-6 free base) FSLLRYNH2 TFA(245329026 free base) inhibitor inhibit

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