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G-418 disulfate
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G-418 disulfate
Catalog No. T6512Cas No. 108321-42-2
G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, an inhibitor of protein synthesis with eukaryotic selectivity. G-418 disulfate blocks peptide synthesis by inhibiting peptide chain elongation.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 mg | $42 | In Stock | |
| 1 g | $50 | In Stock | |
| 5 g | $158 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, an inhibitor of protein synthesis with eukaryotic selectivity. G-418 disulfate blocks peptide synthesis by inhibiting peptide chain elongation. |
| In vitro | Continuous administration of G418 at doses ranging from 40 to 80 mg/kg for three consecutive days is sufficient to eradicate all untransfected Brucella bacterium parasites in infected mice. |
| In vivo | At concentrations ranging from 1 to 300 micrograms/ml, G418 inhibits a variety of prokaryotic and eukaryotic organisms. Typically, concentrations of 5 mg/L or lower are effective against bacteria and algae, while a concentration of 400 mg/L is used for the selection of mammalian cells, and a maintenance concentration for mammalian cells is set at 200 mg/L. |
| Alias | Geneticin, G418 Sulfate, Antibiotic G-418 sulfate, Geneticin sulfate |
| Molecular Weight | 692.71 |
| Formula | C20H40N4O10·2H2O4S |
| Cas No. | 108321-42-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
| Solubility Information | H2O: 43.31mM DMSO: Insoluble | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
H2O
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Keywords
synthesiseukaryoticAntibiotic G-418Geneticin SulfateG418G-418 disulfateAntibiotic G 418Antibiotic G418 SulfateAntibiotic G418BacterialAntibiotic G 418 SulfateInhibitorG 418 SulfateproteinG 418 disulfateinhibitAntibioticG-418G-418 DisulfatecellsG 418Antibiotic G-418 SulfateG418 disulfateG418 DisulfateG 418 DisulfateG-418 Sulfate
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