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JNJ-632

JNJ-632
JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator.
Catalog No. T4475Cas No. 1572510-42-9
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Purity:98.21%
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JNJ-632

Purity: 98.21%
Catalog No. T4475Cas No. 1572510-42-9

JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$38In Stock
10 mg$59In Stock
25 mg$118In Stock
50 mg$193In Stock
100 mg$311In Stock
200 mg$449In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Product Introduction

Bioactivity
Description
JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator.
In vivo
Administration of JNJ-632 (54) in HBV genotype D infected chimeric mice resulted in a 2.77 log reduction of the HBV DNA viral load.
Chemical Properties
Molecular Weight378.42
FormulaC18H19FN2O4S
Cas No.1572510-42-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 125 mg/mL (330.32 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6426 mL13.2128 mL26.4257 mL132.1283 mL
5 mM0.5285 mL2.6426 mL5.2851 mL26.4257 mL
10 mM0.2643 mL1.3213 mL2.6426 mL13.2128 mL
20 mM0.1321 mL0.6606 mL1.3213 mL6.6064 mL
50 mM0.0529 mL0.2643 mL0.5285 mL2.6426 mL
100 mM0.0264 mL0.1321 mL0.2643 mL1.3213 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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