Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 115.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 397.00 | |
25 mg | In stock | $ 663.00 | |
50 mg | In stock | $ 945.00 | |
100 mg | In stock | $ 1,280.00 | |
500 mg | In stock | $ 2,570.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 272.00 |
Description | KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme. |
In vitro | The novel cathepsin L/K inhibitors KGP94 could inhibit in vitro M2 macrophage invasion and reduce the macrophage-stimulated invasion of 4T1 murine breast cancer cells. KGP94 treatment also reduced the expression of several M2-associated markers, suggesting that cathepsin L activity may be important for IL-4-driven M0 to M2 differentiation[1]. |
Synonyms | KGP-94, KGP 94 |
Molecular Weight | 350.23 |
Formula | C14H12BrN3OS |
CAS No. | 1131456-28-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/ml (171.32 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
KGP94 1131456-28-4 Proteases/Proteasome Cysteine Protease KGP-94 Inhibitor M2 marker KGP 94 Metastasis Raw264.7 macrophage metastatic carcinoma Cathepsin inhibit prostate (PC-3ML) Cathepsin L breast cancer cell inhibitor