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LH846

Catalog No. T1877 CAS 639052-78-1

Synonyms: LH-846, LH 846

LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); exhibits no inhibitory activity at CK2.

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LH846, CAS 639052-78-1

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); exhibits no inhibitory activity at CK2.
Targets&IC50	CK1δ:290 nM, CK1α:2.5 μM, CK1ε:1.3 μM

Synonyms	LH-846, LH 846
Molecular Weight	316.8
Formula	C16H13ClN2OS
CAS No.	639052-78-1

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 45 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Lee JW, et al. Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10608-11.

Related Products

Related compounds with same targets

(E/Z)-GO289 Epiblastin A Ellagic acid (hydrate) SR-3029 CK2 inhibitor 2 CKI-7 LH846 PF-5006739

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

LH846 639052-78-1 代谢干细胞 Casein Kinase LH 846 inhibit Inhibitor LH-846 inhibitor

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