Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

LY2922470

Catalog No. T15810Cas No. 1423018-12-5

LY2922470 is a potent, selective G protein-coupled receptor 40 (GPR40) agonist, with EC50s of 7 nM for human GPR40, 1 nM for mouse GPR40 and 3 nM for rat GPR40, respectively. LY2922470 reduces glucose levels along and increases insulin and GLP-1 significantly.

LY2922470

LY2922470

Purity: 96%
Catalog No. T15810Cas No. 1423018-12-5
LY2922470 is a potent, selective G protein-coupled receptor 40 (GPR40) agonist, with EC50s of 7 nM for human GPR40, 1 nM for mouse GPR40 and 3 nM for rat GPR40, respectively. LY2922470 reduces glucose levels along and increases insulin and GLP-1 significantly.
Pack SizePriceAvailabilityQuantity
1 mg$117In Stock
5 mg$249In Stock
10 mg$374In Stock
25 mg$649In Stock
50 mg$926In Stock
100 mg$1,260In Stock
1 mL x 10 mM (in DMSO)$261In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "LY2922470"

Select Batch
Purity:96%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally available agonist of the G protein-cou
Targets&IC50
FFA1/GPR40:1 nM(EC50,mouse), FFA1/GPR40:3 nM(EC50,rat), FFA1/GPR40:7 nM(EC50, human)
Chemical Properties
Molecular Weight475.6
FormulaC28H29NO4S
Cas No.1423018-12-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 125 mg/mL (262.83 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1026 mL10.5130 mL21.0261 mL105.1304 mL
5 mM0.4205 mL2.1026 mL4.2052 mL21.0261 mL
10 mM0.2103 mL1.0513 mL2.1026 mL10.5130 mL
20 mM0.1051 mL0.5257 mL1.0513 mL5.2565 mL
50 mM0.0421 mL0.2103 mL0.4205 mL2.1026 mL
100 mM0.0210 mL0.1051 mL0.2103 mL1.0513 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy LY2922470 | purchase LY2922470 | LY2922470 cost | order LY2922470 | LY2922470 chemical structure | LY2922470 formula | LY2922470 molecular weight