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LY2922470 is a potent, selective G protein-coupled receptor 40 (GPR40) agonist, with EC50s of 7 nM for human GPR40, 1 nM for mouse GPR40 and 3 nM for rat GPR40, respectively. LY2922470 reduces glucose levels along and increases insulin and GLP-1 significantly.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $117 | In Stock | |
5 mg | $249 | In Stock | |
10 mg | $374 | In Stock | |
25 mg | $649 | In Stock | |
50 mg | $926 | In Stock | |
100 mg | $1,260 | In Stock | |
1 mL x 10 mM (in DMSO) | $261 | In Stock |
Description | LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally available agonist of the G protein-cou |
Targets&IC50 | FFA1/GPR40:1 nM(EC50,mouse), FFA1/GPR40:3 nM(EC50,rat), FFA1/GPR40:7 nM(EC50, human) |
Molecular Weight | 475.6 |
Formula | C28H29NO4S |
Cas No. | 1423018-12-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 125 mg/mL (262.83 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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