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Lonapalene

Lonapalene
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Purity:98.82%
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Lonapalene

Catalog No. T16802Cas No. 91431-42-4
Lonapalene (RS4317) is a 5-lipoxygenase (5-LO) inhibitor with anti-psoriasis efficacy.Lonapalene topically blocks skin inflammation.
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Pack SizePriceAvailabilityQuantity
1 mg$179In Stock
5 mg$538In Stock
10 mg$786In Stock
25 mg$1,190In Stock
50 mg$1,590In Stock
100 mg$2,180In Stock
1 mL x 10 mM (in DMSO)$589In Stock
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Product Introduction

Bioactivity
Description
Lonapalene (RS4317) is a 5-lipoxygenase (5-LO) inhibitor with anti-psoriasis efficacy.Lonapalene topically blocks skin inflammation.
In vitro
Clonaparine (RS4317) is used to treat psoriasis, and leukotriene B4-related mediators [1].
AliasRS4317
Chemical Properties
Molecular Weight338.74
FormulaC16H15ClO6
Cas No.91431-42-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 80 mg/mL (236.17 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9521 mL14.7606 mL29.5212 mL147.6058 mL
5 mM0.5904 mL2.9521 mL5.9042 mL29.5212 mL
10 mM0.2952 mL1.4761 mL2.9521 mL14.7606 mL
20 mM0.1476 mL0.7380 mL1.4761 mL7.3803 mL
50 mM0.0590 mL0.2952 mL0.5904 mL2.9521 mL
100 mM0.0295 mL0.1476 mL0.2952 mL1.4761 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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