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MLS000532223

Catalog No. T8473 CAS 16616-39-0

MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).

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MLS000532223, CAS 16616-39-0

Pack Size	Availability	Price/USD
1 mg	In stock	$ 132.00
2 mg	In stock	$ 193.00
5 mg	In stock	$ 323.00
10 mg	In stock	$ 486.00
25 mg	In stock	$ 795.00
50 mg	In stock	$ 1,090.00
100 mg	In stock	$ 1,490.00
1 mL * 10 mM (in DMSO)	In stock	$ 335.00

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Purity: 98.11%

Biological Description

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Description	MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).
Targets&IC50	Rho family GTPases:16-120 μM(EC50)
In vitro	MLS000532223, a general inhibitor that prevents GTP binding to several GTPases in a dose-dependent manner and is active in biochemical and cell-based secondary assays.?Live-cell imaging and confocal microscopy studies revealed the inhibitor-induced actin reorganization and cell morphology changes, characteristic of Rho GTPases inhibition.

Molecular Weight	251.24
Formula	C15H9NO3
CAS No.	16616-39-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45 mg/mL (179.11 mM), Sonication is recommended.

References and Literature

1. Zurab Surviladze, et al. Identification of a Small GTPase Inhibitor Using a High-Throughput Flow Cytometry Bead-Based Multiplex Assay. J Biomol Screen. 2010 Jan;15(1):10-20.

Related compound libraries

This product is contained In the following compound libraries：

Kinase Inhibitor Library Membrane Protein-targeted Compound Library GPCR Compound Library Inhibitor Library MAPK Inhibitor Library Anti-Cancer Metabolism Compound Library Anti-Liver Cancer Compound Library Reprogramming Compound Library Anti-Colorectal Cancer Compound Library Bioactive Compound Library

Related Products

Related compounds with same targets

NSC 23766 trihydrochloride Rac1 Inhibitor W56 acetate(1095179-01-3 free base) Rhosin SAR407899 EHT 1864 AZA1 GGTI 2147 CCG-100602

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MLS000532223 16616-39-0 Cell Cycle/Checkpoint GPCR/G Protein MAPK Rho Ras GTPases Inhibitor Rab cytoskeleton MLS 000532223 actin Rho GTPases MLS-000532223 inhibit inhibitor

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