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Nelonemdaz
🥰Excellent
Catalog No. T16286Cas No. 640290-67-1
Alias Salfaprodil free base, Neu2000
Nelonemdaz (Neu2000) is an NMDA receptor antagonist with antioxidant activity and neuroprotective activity used in the study of cerebral infarction reperfusion injury and acute ischemic stroke.
Nelonemdaz
🥰Excellent
Purity: 98.95%
Catalog No. T16286Alias Salfaprodil free base, Neu2000Cas No. 640290-67-1
Nelonemdaz (Neu2000) is an NMDA receptor antagonist with antioxidant activity and neuroprotective activity used in the study of cerebral infarction reperfusion injury and acute ischemic stroke.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $64 | In Stock | |
| 5 mg | $198 | In Stock | |
| 10 mg | $372 | In Stock | |
| 25 mg | $689 | In Stock | |
| 50 mg | $987 | In Stock | |
| 100 mg | $1,530 | In Stock | |
| 500 mg | $2,970 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $173 | In Stock |
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Purity:98.95%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Nelonemdaz (Neu2000) is an NMDA receptor antagonist with antioxidant activity and neuroprotective activity used in the study of cerebral infarction reperfusion injury and acute ischemic stroke. |
| In vitro | Nelonemdaz (0.19-12.5 μM) dose-dependently reduces the amount of reactive oxygen species/nitrogen species (ROS/RNS) formation induced by Antimycin A and inhibits the formation of malondialdehyde (MDA)[3]. |
| In vivo | In male Sprague-Dawley rats weighing 260 to 300 g (subjected to the clip occlusion model), Nelonemdaz (0.5-20 mg/kg; intravenous administration 5 minutes after reperfusion) exhibited significant neuroprotective effects[1]. |
| Alias | Salfaprodil free base, Neu2000 |
| Molecular Weight | 383.22 |
| Formula | C15H8F7NO3 |
| Cas No. | 640290-67-1 |
| Smiles | OC(=O)c1cc(NCc2c(F)c(F)c(c(F)c2F)C(F)(F)F)ccc1O |
| Relative Density. | 1.659 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100 mg/mL (260.95 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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