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Niridazole
Niridazole (Ambilhar) is an antiparasitic compound belonging to nitroimidazoles. Niridazole is primarily used to treat schistosomiasis, which kills the parasite by interfering with its metabolism. Niridazole rapidly concentrates in the parasite, inhibits egg and sperm production, and inhibits phosphofructokinase activity.
Catalog No. T28174Cas No. 61-57-4
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Purity:98.90%
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Niridazole
Catalog No. T28174Alias BA-32644, BA32644, BA 32644, AmbilharCas No. 61-57-4
Niridazole (Ambilhar) is an antiparasitic compound belonging to nitroimidazoles. Niridazole is primarily used to treat schistosomiasis, which kills the parasite by interfering with its metabolism. Niridazole rapidly concentrates in the parasite, inhibits egg and sperm production, and inhibits phosphofructokinase activity.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $397 | In Stock | |
| 5 mg | $970 | In Stock | |
| 10 mg | $1,290 | In Stock | |
| 25 mg | $1,950 | In Stock | |
| 50 mg | $2,620 | In Stock | |
| 100 mg | $3,530 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Niridazole (Ambilhar) is an antiparasitic compound belonging to nitroimidazoles. Niridazole is primarily used to treat schistosomiasis, which kills the parasite by interfering with its metabolism. Niridazole rapidly concentrates in the parasite, inhibits egg and sperm production, and inhibits phosphofructokinase activity. |
| In vitro | The minimum inhibitory concentrations for niridazole ranged from 0.0037 to 1.0 microgram/ml [1] |
| In vivo | Niridazole, a human anthelminthic drug, is shown to be a potent long-acting suppressor of delayed hypersensitivity. Much lower doses than used in the therapy of helminth infections suppressed granuloma formation around Schistosoma mansoni eggs for periods up to 32 days and inhibited delayed footpad swelling in mice previously sensitized with eggs. Marked prolongation of skin allograft survival in mice across the H-2 area was produced.[2] |
| Alias | BA-32644, BA32644, BA 32644, Ambilhar |
| Molecular Weight | 214.2 |
| Formula | C6H6N4O3S |
| Cas No. | 61-57-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO: 1 mg/mL, Sonication is recommended.  |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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