Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A) (IC50s: 0.86 and 1.3 μM, respectively). Opiranserin displays antagonistic activity on rP2X3 (IC50=0.87 μM).
Description | Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A) (IC50s: 0.86 and 1.3 μM, respectively). Opiranserin displays antagonistic activity on rP2X3 (IC50=0.87 μM). |
Targets&IC50 | rP2X3:0.87 μM, 5-HT2A Receptor:1.3 μM, GlyT2:0.86 μM |
Synonyms | Glycine transporters, postoperative, VVZ-149, Serotonin Receptor, 5-hydroxytryptamine Receptor, VVZ 149, pain, GlyT, Inhibitor, non-opioid, P2XRs, Opiranserin, 5-HT Receptor, anti-inflammatory, VVZ149, analgesic, P2X Receptor, inhibit |
Molecular Weight | 394.51 |
Formula | C21H34N2O5 |
CAS No. | 1441000-45-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
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