Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rate of cholesterol synthesis in CHO cells (IC50 = 0.53 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 37.00 | |
2 mg | In stock | $ 50.00 | |
5 mg | In stock | $ 100.00 | |
10 mg | In stock | $ 183.00 | |
25 mg | In stock | $ 405.00 | |
50 mg | In stock | $ 590.00 | |
100 mg | In stock | $ 859.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 100.00 |
Description | PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rate of cholesterol synthesis in CHO cells (IC50 = 0.53 μM). |
Targets&IC50 | SREBP:0.175 μM |
Molecular Weight | 409.56 |
Formula | C25H35N3O2 |
CAS No. | 947303-87-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 24.1 mg/mL(50 mM)
You can also refer to dose conversion for different animals. More
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PF 429242 947303-87-9 Membrane transporter/Ion channel Metabolism NPC1L1 Lipid PF-429242 PF429242 inhibitor inhibit