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PPI-1019

Catalog No. T28441Cas No. 290828-45-4
Alias PPI1019, Apan

PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).

PPI-1019

PPI-1019

Purity: 97.21%
Catalog No. T28441Alias PPI1019, ApanCas No. 290828-45-4
PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).
Pack SizePriceAvailabilityQuantity
1 mg$350In Stock
5 mg$828In Stock
10 mg$1,130In Stock
25 mg$1,590In Stock
50 mg$1,980In Stock
100 mg$2,500In Stock
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Purity:97.21%
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Product Introduction

Bioactivity
Description
PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).
Targets&IC50
β-Amyloid (1–42):1.6 μM
In vitro
The MTT data for the PPI-1019 using SHY5Y cells after a 24 h aggregation of 10 μM Aβ-(1–42) with IC50 was 10 μM. The N-methylated peptides PPI-1019 show a reduction in cell toxicity at concentrations similar to that used in the thioflavin T assays (IC50=1.6 μM).[1]
AliasPPI1019, Apan
Chemical Properties
Molecular Weight650.85
FormulaC36H54N6O5
Cas No.290828-45-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 1 mg/mL, Sonication is recommended.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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