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Ravuconazole
🥰Excellent
Catalog No. T7152Cas No. 182760-06-1
Alias ER-30346, BMS-207147
Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.
Ravuconazole
🥰Excellent
Purity: 99.84%
Catalog No. T7152Alias ER-30346, BMS-207147Cas No. 182760-06-1
Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | 32 € | In Stock | |
| 10 mg | 56 € | In Stock | |
| 25 mg | 126 € | In Stock | |
| 50 mg | 226 € | In Stock | |
| 100 mg | 329 € | In Stock | |
| 200 mg | 472 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 35 € | In Stock |
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Purity:99.84%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi. |
| In vitro | The in vitro activity of Ravuconazole against 80 clinical isolates of Aspergillus was compared with that of itraconazole and amphotericin B, using a validated microtiter method.Geometric mean MICs (in microg/ml) were as follows: 1.71 for Ravuconazole, 0.67 for itraconazole, and 0.63 for amphotericin B. The range of concentrations of each drug was 0.125 to >16 microg/ml.Aspergillus fumigatus was significantly more susceptible to Ravuconazole (P < 0.05) than A. terreus and A. flavus.No Ravuconazole-resistant A. fumigatus isolates were identified, though eight itraconazole-resistant (MIC, >8 microg/ml) isolates were.Ravuconazole is active against Aspergillus spp. at slightly high concentrations compared with itraconazole and amphotericin B[1]. |
| Alias | ER-30346, BMS-207147 |
| Molecular Weight | 437.47 |
| Formula | C22H17F2N5OS |
| Cas No. | 182760-06-1 |
| Smiles | C[C@@H](c1nc(cs1)-c1ccc(cc1)C#N)[C@](O)(Cn1cncn1)c1ccc(F)cc1F |
| Relative Density. | 1.38g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (114.29 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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