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Recilisib
Recilisib (ON 01210) is a radioprotectant that activates AKT and PI3K activities in cells.
Catalog No. T13862Cas No. 334969-03-8
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Purity:99.84%
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Recilisib
Catalog No. T13862Alias Ex-RAD, ON 01210Cas No. 334969-03-8
Recilisib (ON 01210) is a radioprotectant that activates AKT and PI3K activities in cells.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $38 | In Stock | |
| 2 mg | $54 | In Stock | |
| 5 mg | $89 | In Stock | |
| 10 mg | $122 | In Stock | |
| 25 mg | $197 | In Stock | |
| 50 mg | $372 | In Stock | |
| 100 mg | $556 | In Stock | |
| 500 mg | $1,220 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $107 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
| Description | Recilisib (ON 01210) is a radioprotectant that activates AKT and PI3K activities in cells. |
| In vitro | Recilisib Sodium increases PI3K activity in HFL-1 cells and murine bone marrow cells in response to radiation exposure. Recilisib Sodium treatment in combination with radiation alters the MAPK signaling pathway. |
| In vivo | the rate of recovery and differentiation of primitive bone marrow myeloid progenitor cells in mice significantly increased by Recilisib Sodium. Recilisib Sodium in combination with radiation reduces CFU numbers in mice, but the Recilisib Sodium-treated mice consistently retain a capability to form differentiated colonies. Recilisib Sodium treated mice have a progenitor cell population that is never completely depleted by radiation exposure. |
| Alias | Ex-RAD, ON 01210 |
| Molecular Weight | 336.79 |
| Formula | C16H13ClO4S |
| Cas No. | 334969-03-8 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (148.46 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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