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Relugolix

Catalog No. T3630 CAS 737789-87-6

Synonyms: TAK-385, RVT-601

Purity 98.85% Datasheet

Relugolix is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively binds to and blocks the GnRH receptor in the anterior pituitary gland, which both prevents GnRH binding to the GnRH receptor and inhibits the secretion and release of both luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone from Leydig cells in the testes. Since testosterone is required to sustain prostate growth, reducing testosterone levels may inhibit hormone-dependent prostate cancer cell proliferation.

Relugolix, CAS 737789-87-6

Pack Size	Availability	Price/USD
1 mg	In stock	60.00
5 mg	In stock	110.00
10 mg	In stock	180.00
25 mg	In stock	360.00
50 mg	In stock	468.00
1 mL * 10 mM (in DMSO)	In stock	180.00

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Purity 98.64%

HNMR HPLC COA Datasheet MSDS

Purity 98.85%

HNMR HPLC COA Datasheet MSDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Targets&IC50

GNRHR,

Synonyms	TAK-385 , RVT-601
Purity	98.64%
Molecular Weight	623.63
Formula	C29H27F2N7O5S
CAS No.	737789-87-6

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 55 mg/mL (88.2 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. MacLean DB et al. J Clin Endocrinol Metab. 2015 Dec;100(12):4579-87. 2. Nakata D et al. Eur J Pharmacol. 2014 Jan 15;723:167-74.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library Inhibitor Library Anti-cancer Compound Library Clinical Compound Library Neuronal Signaling Compound Library GPCR Compound Library Anti-cancer Clinical Compound Library Fluorochemical Library

Related Products

Related compounds with same targets

Degarelix Danazol Relugolix Goserelin acetate Leuprorelin Leuprolide Acetate Elagolix sodium Cetrorelix

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.