Powder: -20°C for 3 years | In solvent: -80°C for 1 year
S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 64.00 | |
25 mg | In stock | $ 128.00 | |
50 mg | In stock | $ 197.00 | |
100 mg | In stock | $ 322.00 | |
200 mg | In stock | $ 478.00 | |
500 mg | In stock | $ 772.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 43.00 |
Description | S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats. |
Targets&IC50 | Androgen Receptor:1.7 nM(Ki) |
In vitro | Administration of 10 nM S-23 induces AR-mediated transcriptional activation in CV-1 cells [2]. |
In vivo | Administration of S-23 to castrated animals increases the weights of the androgen-dependent organ dose-dependently with the ED50s of S-23 in the prostate and levator ani muscle of 0.43 and 0.079 mg/d, respectively[2]. |
Synonyms | (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide, S23 |
Molecular Weight | 416.75 |
Formula | C18H13ClF4N2O3 |
CAS No. | 1010396-29-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 88 mg/mL (211.16 mM)
You can also refer to dose conversion for different animals. More
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S-23 1010396-29-8 Endocrinology/Hormones Androgen Receptor activation levator castrated S 23 ani Inhibitor (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide vesicle cells transcriptional muscle prostate S23 seminal CV-1 inhibit inhibitor