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T16Ainh-A01
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T16Ainh-A01
Catalog No. T13059Cas No. 552309-42-9
T16Ainh-A01 is a potent inhibitor of TMEM16A Chloride channel, inhibiting TMEM16A-mediated chloride currents (IC50 of 1 μM),and functions as a calcium-activated chloride channel (CaCC).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $67 | In Stock | |
| 10 mg | $108 | In Stock | |
| 25 mg | $215 | In Stock | |
| 50 mg | $397 | In Stock | |
| 100 mg | $589 | In Stock | |
| 200 mg | $843 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | T16Ainh-A01 is a potent inhibitor of TMEM16A Chloride channel, inhibiting TMEM16A-mediated chloride currents (IC50 of 1 µM),and functions as a calcium-activated chloride channel (CaCC). |
| In vitro | T16Ainh-A01 (0.3-30μM) can significantly reduce the inward and outward components of IClCa and inhibit IClCa in RUICC without significantly affecting L-type Ca2+ current[1]. T16Ainh-A01 (10 μM) inhibits nearly completely TMEM16A chloride current (induced by 275 nM free calcium in the pipette) at all voltages, indicating a voltage-independent block mechanism[2]. |
| Molecular Weight | 416.52 |
| Formula | C19H20N4O3S2 |
| Cas No. | 552309-42-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: Insoluble  DMF: 10 mg/mL (24.01 mM) DMSO: 4 mg/mL(9.6 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
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