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TMP195

TMP195 (TFMO 2) is a selective class IIa histone deacetylase (HDAC) inhibitor.

Catalog No. T3983Cas No. 1314891-22-9

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Purity:98.92%

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COA HNMR HPLC LCMS

TMP195

Catalog No. T3983Cas No. 1314891-22-9

TMP195 (TFMO 2) is a selective class IIa histone deacetylase (HDAC) inhibitor.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
2 mg	$67	In Stock
5 mg	$112	In Stock
10 mg	$189	In Stock
25 mg	$379	In Stock
50 mg	$455	In Stock
100 mg	$669	In Stock
1 mL x 10 mM (in DMSO)	$112	In Stock

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Product Introduction

Bioactivity

Description	TMP195 (TFMO 2) is a selective class IIa histone deacetylase (HDAC) inhibitor.
Targets&IC50	HDAC5:60 nM(Ki), HDAC9:15 nM(Ki), HDAC7:26 nM(Ki), HDAC4:59 nM(Ki)
Alias	TFMO 2, TMP 195

Chemical Properties

Molecular Weight	456.42
Formula	C₂₃H₁₉F₃N₄O₃
Cas No.	1314891-22-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 82 mg/mL (179.7 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1910 mL	10.9548 mL	21.9096 mL	109.5482 mL
5 mM	0.4382 mL	2.1910 mL	4.3819 mL	21.9096 mL
10 mM	0.2191 mL	1.0955 mL	2.1910 mL	10.9548 mL
20 mM	0.1095 mL	0.5477 mL	1.0955 mL	5.4774 mL
50 mM	0.0438 mL	0.2191 mL	0.4382 mL	2.1910 mL
100 mM	0.0219 mL	0.1095 mL	0.2191 mL	1.0955 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc