Shopping Cart
- Remove All
- Your shopping cart is currently empty
TP0427736 is a potent and selective inhibitor of ALK5 with an IC50 of 2.72 nM, 300-fold higher than the inhibitory effect on ALK3. TP0427736 reduces TGF-β-induced growth inhibition in human outer root sheath cells and elongates the anagen phase in mouse hair follicles.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $97 | In Stock | |
5 mg | $238 | In Stock | |
10 mg | $389 | In Stock | |
25 mg | $663 | In Stock | |
50 mg | $945 | In Stock | |
1 mL x 10 mM (in DMSO) | $269 | In Stock |
Description | TP-0427736 is a novel potent and selective ALK5 inhibitor (IC50: 2.72 nM). P0427736 was 300-fold higher than the inhibitory effect on ALK3. TP0427736 reduces TGF-β induced growth inhibition in human outer root sheath cells and elongates the anagen phase i |
Targets&IC50 | ALK5:2.72 nM |
Alias | TP-427736, TP427736, TP-0427736 |
Molecular Weight | 298.39 |
Formula | C14H10N4S2 |
Cas No. | 864374-00-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 65 mg/ml (217.84 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.