-20℃ 3 years powder
-80℃ 2 years in solvent
Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | 50.00 | |
5 mg | In stock | 80.00 | |
1 mL * 10 mM (in DMSO) | In stock | 80.00 |
Description | Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome. |
Targets&IC50 |
Synonyms | Somalgen , Somalgen |
Purity | 98.00% |
Molecular Weight | 414.33 |
Formula | C21H13F3N2O4 |
CAS No. | 66898-62-2 |
-20℃ 3 years powder
-80℃ 2 years in solvent
DMSO: 10 mg/mL
( < 1 mg/ml refers to the product slightly soluble or insoluble )
Safe and effective drug dosing is necessary, regardless of its purpose of administration. Learn More
bottom
Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.