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Ani9

🥰Excellent
Catalog No. T26630Cas No. 356102-14-2
Alias Apelin-12 acetate (229961-08-4 Free base), Ani-9, Ani 9

Ani9 is a high selective blocker of Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A) with an IC50 of 77 nM and can be used in studies about ANO1 and the treatment of ancer, hypertension, pain, diarrhea and asthma.

Ani9

Ani9

🥰Excellent
Purity: 98.72%
Catalog No. T26630Alias Apelin-12 acetate (229961-08-4 Free base), Ani-9, Ani 9Cas No. 356102-14-2
Ani9 is a high selective blocker of Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A) with an IC50 of 77 nM and can be used in studies about ANO1 and the treatment of ancer, hypertension, pain, diarrhea and asthma.
Pack SizePriceAvailabilityQuantity
1 mg$33In Stock
5 mg$76In Stock
10 mg$133In Stock
25 mg$283In Stock
50 mg$478In Stock
100 mg$689In Stock
500 mg$1,480In Stock
1 mL x 10 mM (in DMSO)$84In Stock
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Purity:98.72%
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Product Introduction

Bioactivity
Description
Ani9 is a high selective blocker of Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A) with an IC50 of 77 nM and can be used in studies about ANO1 and the treatment of ancer, hypertension, pain, diarrhea and asthma.
AliasApelin-12 acetate (229961-08-4 Free base), Ani-9, Ani 9
Chemical Properties
Molecular Weight332.78
FormulaC17H17ClN2O3
Cas No.356102-14-2
SmilesCOc1ccccc1\C=N\NC(=O)COc1ccc(Cl)cc1C
Relative Density.1.20 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 16.6 mg/mL (50 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0050 mL15.0249 mL30.0499 mL150.2494 mL
5 mM0.6010 mL3.0050 mL6.0100 mL30.0499 mL
10 mM0.3005 mL1.5025 mL3.0050 mL15.0249 mL
20 mM0.1502 mL0.7512 mL1.5025 mL7.5125 mL
50 mM0.0601 mL0.3005 mL0.6010 mL3.0050 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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