apelin-12 acetate

Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 MAPK signaling pathway of the apoptosis-related MAPKs family, thus offering protection to neurons.

Palmitoyl Hexapeptide-12 Acetate (Palmitoyl Hexapeptide-12 Acetate (171263-26-6 Free base)) can promote collagen, elastin, and hyaluronic acid on proliferation. It can be used to improve the skin's water content, increase the thickness of the dermis, reduce microgrooves.

PAMP-12 (human, porcine) acetate (PAMP-12 (human, porcine) acetate (196305-05-2 free base)) , a major component of ir-PAMP, is processed from the AM precursor, as is PAMP-20, and may participate in cardiovascular control.

Apelin-17 (human, bovine) acetate is an endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).

Myristoyl Tetrapeptide-12 Acetate (Myristoyl Tetrapeptide-12 Acetate (959610-24-3 Free base)) , the reaction product of myristic acid and Tetrapeptide-12, is a peptide stimulating hair and eyelash growth and enhancing the appearance of eyelashes and/or eyebrows. Myristoyl tetrapeptide-12 can increase keratinocyte proliferation improve appearance, firmness elasticity, and skin thickness.

ZIP acetate is a novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-ph

AUNP-12 acetate is a polypeptide inhibitor of PD-1 that is equivalent to PD-1 and PD-2 in inhibiting lymphocyte proliferation and effector fuction, in addition to immune activation and antitumor activity.

Apelin-12 is a highly potent C-terminal fragment of a polypeptide that exhibits a strong affinity towards the orphan receptor APJ. It plays a role in maintaining body fluid balance and regulating feeding control in the central nervous system. Additionally, Apelin-12 functions as an inhibitor of HIV-1 entry through the APJ receptor and demonstrates neuroprotective properties.

(Ala13)-Apelin-13 acetate, an APJ antagonist, modulates CRF-induced enhanced colonic motility, visceral sensation, and gut barrier.