Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 52.00 | |
2 mg | In stock | $ 70.00 | |
5 mg | In stock | $ 88.00 | |
10 mg | In stock | $ 126.00 | |
25 mg | In stock | $ 239.00 | |
50 mg | In stock | $ 401.00 | |
100 mg | In stock | $ 597.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 126.00 |
Description | Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM. |
Targets&IC50 | SIRT2:28 nM |
Cell Research | Human MCF-7 cells are grown in DMEM media contained 10% (vol/vol) heat-inactivated fetal bovine serum and 1% penicillin-streptomycin and treated with in the presence of 200 nM TSA for 6 hr. The acetylation level of p53 protein is determined by western blot using anti-acetyl-p53 (K382) antibody. β-actin serves as a loading control. (Only for Reference) |
Molecular Weight | 581.85 |
Formula | C34H51N3O3S |
CAS No. | 1429749-41-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (171.87 mM)
Chloroform: Soluble
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Thiomyristoyl 1429749-41-6 Chromatin/Epigenetic DNA Damage/DNA Repair Sirtuin Inhibitor inhibit inhibitor