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Tylosin

Catalog No. T1003 CAS 1401-69-0

Synonyms: Fradizine, Tylosin A, Tylosine, Tylocine

Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.

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Tylosin, CAS 1401-69-0

Pack Size	Availability	Price/USD
25 mg	In stock	$ 46.00
50 mg	In stock	$ 59.00
100 mg	In stock	$ 72.00
500 mg	In stock	$ 176.00
1 mL * 10 mM (in DMSO)	In stock	$ 30.00

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Purity: mixture

Biological Description

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Description

Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.

In vivo

Tylosin and its phosphate and tartrate salts are used in pigs, cattle and poultry for the treatment of infections caused by organisms sensitive to tylosin. They mav be administered to calves oralv in the milk renlacer at a dose ot 40 moiko body weight (bw) and to cattle, by intramuscular injection, at a dose of 4-10 mg/kg bw. It may be administered in the drinking-water af a dose of 25 mg/kg bw, in the feed at a dose of 3-7 mg/kg bw or by intramuscularl injection at a dose of 2-10 mg/kg bw. Tylosin is administered to poultry in thel drinking-water at a dose equivalent to 75 mg/kg bw. It is used primarily in thel treatment of chronic respiratory diseasecomplex in chickens and infectioussinusitis in turkeys caused by Mycoplasma gallisepticum.

Synonyms	Fradizine, Tylosin A, Tylosine, Tylocine
Molecular Weight	916.1
Formula	C46H77NO17
CAS No.	1401-69-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 91 mg/mL(99.3 mM)

References and Literature

1. Entorf M, et al. Tylosin susceptibility of staphylococci from bovine mastitis. Vet Microbiol. 2014 Jul 16;171(3-4):368-73. 2. Pilcher CM, et al. Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. J Anim Sci. 2013 Dec;91(12):5687-95.

Related compound libraries

This product is contained In the following compound libraries：

Microbial Natural Product Library Human Endogenous Metabolite Compound Library Plus Anti-Bacterial Compound Library Anti-Infection Compound Library Anti-infective Natural Product Library Human Metabolite Library Bioactive Compounds Library Max Covalent Natural Product Library Covalent Inhibitor Library Bioactive Compound Library

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Dose Conversion

You can also refer to dose conversion for different animals. More

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tylosin 1401-69-0 Microbiology/Virology Antibacterial Antibiotic diseases Fradizine inhibit Tylosin A Inhibitor infections mycoplasma Bacterial respiratory mastitis veterinary atrophic Tylosine Tylocine poultry rhinitis dysentery inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.