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Tylosin tartrate

Catalog No. T0861 CAS 74610-55-2

Tylosin tartrate, a macrolide antibiotic, is approved for the control of mycoplasmosis in poultry.

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Tylosin tartrate, CAS 74610-55-2

Pack Size	Availability	Price/USD
25 mg	In stock	$ 39.00
50 mg	In stock	$ 57.00
100 mg	In stock	$ 75.00
200 mg	In stock	$ 122.00
500 mg	In stock	$ 198.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Purity: 99.16%

Purity: 91.82%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Tylosin tartrate, a macrolide antibiotic, is approved for the control of mycoplasmosis in poultry.
In vitro	After intravenous administration of 10 mg/kg Tylosin tartrate, dehydrated camels exhibit significantly higher serum drug concentrations, reduced volume of distribution, and lower clearance rates, with a marked decrease in overall drug elimination speed when compared to normal camels. Furthermore, dehydrated camels receiving a 20 mg/kg dose of Tylosin tartrate via intramuscular injection show reduced average absorption time and lower drug concentrations in the serum. Treatment of neonatal piglets with oral Tylosin tartrate (50 mg/kg, twice daily) for 10 consecutive days, starting 14 days post-intranasal infection, significantly mitigates the severity and incidence of gross pulmonary lesions. Tylosin enhances splenocyte proliferation, yielding higher levels of proliferation in the conditioned medium than in chicken whole spleen cell cultures. Additionally, Tylosin increases the anti-tumor activity of chicken splenic cells.
In vivo	Compared to the control group, Tylosin tartrate (25 mg/L) significantly inhibited methane production, indicating that the concentrations commonly found in swine lagoons negatively affect anaerobic metabolism. In anaerobic incubated sludge, the 90% clearance times for Tylosin, its derivatives Tilmicosin and Relomycin ranged from 30 to 130 hours; this reduced to 12 to 26 hours post aeration. The degradation of Tylosin followed a biphasic pattern with a rapid initial loss followed by a slower elimination phase. Under storage conditions in Milli-Q water (pH 5.7–6.7) at 22°C, Tylosin tartrate remained stable for at least one month.

Molecular Weight	1052.16
Formula	C46H77NO17·1/2C4H6O6
CAS No.	74610-55-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 183 mg/mL (173.9 mM)

DMSO: 276 mg/mL (262.3 mM)

Ethanol: 179 mg/mL(170.1 mM)

References and Literature

1. Loftin KA, et al. Environ Toxicol Chem, 2005, 24(4), 782-788. 2. Kolz AC, et al. Water Environ Res, 2005, 77(1), 49-56. 3. Baba T, et al. Poult Sci, 1998, 77(9), 1306-13011. 4. Hannan PC, et al. Res Vet Sci, 1982, 33(1), 76-88. 5. Ziv G, et al. J Vet Pharmacol Ther, 1995, 18(4), 299-305.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Microbial Natural Product Library Bioactive Compounds Library Max Bioactive Compound Library FDA-Approved & Pharmacopeia Drug Library Macrocyclic Compound Library Approved Drug Library Natural Product Library NO PAINS Compound Library Anti-infective Natural Product Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tylosin tartrate 74610-55-2 Microbiology/Virology Antibacterial Antibiotic diseases veterinary Tylosin Bacterial poultry mastitis Inhibitor infections inhibit dysentery rhinitis respiratory Tylosin Tartrate atrophic mycoplasma inhibitor

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