Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 278.00 | |
2 mg | In stock | $ 413.00 | |
5 mg | In stock | $ 689.00 | |
10 mg | In stock | $ 979.00 | |
25 mg | In stock | $ 1,460.00 | |
50 mg | In stock | $ 1,960.00 | |
100 mg | In stock | $ 2,650.00 |
Description | VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V. |
In vitro | VBY-825 is a potent assayed cathepsins inhibitor and its potency against at least one cathepsin, cathepsin S, extends across species relevant for pharmacology studies, specifically mouse. 10 mg/kg/day dose of VBY-825 achieves a trough plasma concentration >200nM, which is well above that required for full inhibition of the intracellular activity of cathepsins B, F, K, L, S and V in both mouse and human cell lines. |
Molecular Weight | 535.55 |
Formula | C23H29F4N3O5S |
CAS No. | 1310340-58-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (233.40 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
VBY-825 1310340-58-9 Proteases/Proteasome Cysteine Protease Cathepsin Inhibitor VBY825 VBY 825 inhibit inhibitor