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Vitexin

Catalog No. T6S1369   CAS 3681-93-4
Synonyms: Apigenin-8-C-glucoside

1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can either inhibit or induce activities of CYP2C11 and CYP3A1. 5. Vitexin induces the novel p53-dependent metastatic and apoptotic pathway. 6. Vitexin protects brain against cerebral I/R injury, and this effect may be regulated by mitogen-activated protein kinase (MAPK) and apoptosis signaling pathways.

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Vitexin Chemical Structure
Vitexin, CAS 3681-93-4
Pack Size Availability Price/USD Quantity
5 mg In stock $ 47.00
10 mg In stock $ 80.00
25 mg In stock $ 153.00
50 mg In stock $ 248.00
100 mg In stock $ 369.00
1 mL * 10 mM (in DMSO) In stock $ 52.00
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Purity: 99.64%
Purity: 99.43%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can either inhibit or induce activities of CYP2C11 and CYP3A1. 5. Vitexin induces the novel p53-dependent metastatic and apoptotic pathway. 6. Vitexin protects brain against cerebral I/R injury, and this effect may be regulated by mitogen-activated protein kinase (MAPK) and apoptosis signaling pathways.
Source
Synonyms Apigenin-8-C-glucoside
Molecular Weight 432.38
Formula C21H20O10
CAS No. 3681-93-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 43 mg/mL(99.4 mM)

Ethanol: Soluble

TargetMolReferences and Literature

1. Can ÖD1, Demir Özkay Ü, Üçel Uİ.. Anti-depressant-like effect of vitexin in BALB/c mice and evidence for the involvement of monoaminergic mechanisms[J]. European Journal of Pharmacology, 2013, 699(1-3):250-257.

TargetMolCitations

1. Jang S A, Hwang Y H, Yang H, et al. Ethanolic extract of Pyrrosia lingua (Thunb.) Farw. ameliorates OVX-induced bone loss and RANKL-induced osteoclastogenesis. Biomedicine & Pharmacotherapy. 2022, 147: 112640. 2. Jung M A, Song H K, Jo K, et al.Gleditsia sinensis Lam. aqueous extract attenuates nasal inflammation in allergic rhinitis by inhibiting MUC5AC production through suppression of the STAT3/STAT6 pathway.Biomedicine & Pharmacotherapy.2023, 161: 114482.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Active Compound Library Tobacco Monomer Library Miao medicine Compound Library Glycometabolism Compound Library Antioxidant Compound Library Traditional Mongolian Medicine Compound Library PBCRBS Traditional Chinese Medicine Compound Library Polyphenolic Natural Product Library Natural Product Library Bioactive Compound Library

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Keywords

Vitexin 3681-93-4 oxidation-reduction Antioxidant neurodegeneration anti-cancer anti-nociceptive inhibit Medicinal anti-hypertensive anti-spasmodic Autophagy Inhibitor anti-viral anti-oxidant antiinflammatory plants Apigenin-8-C-glucoside inhibitor

 

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