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Xanthine

Catalog No. T0665 CAS 69-89-6

Synonyms: 2,6-Dihydroxypurine, Isoxanthine

Xanthine (Isoxanthine) is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Xanthine is found in most body tissues and fluids in various organisms. Biologically Xanthine is produced from guanine by cypin (guanine deaminase). Furthermore, Xanthines act as antagonists for adenosine receptors, with selectivity depending on whether there are substitution of alkyl groups.

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Xanthine, CAS 69-89-6

Pack Size	Availability	Price/USD
500 mg	In stock	$ 42.00
1 g	Inquiry	$ 50.00
1 mL * 10 mM (in DMSO)	In stock	$ 46.00

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Purity: 89.06%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	2,6-Dihydroxypurine, Isoxanthine
Molecular Weight	152.11
Formula	C5H4N4O2
CAS No.	69-89-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 1.52 mg/mL (10 mM), Sonification is recommended

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: < 1 mg/mL (insoluble or slightly soluble)

References and Literature

1. SMITH SC, et al. The use of amberlite resin in a separation of xanthine and guanine. J Am Chem Soc. 1948 Nov;70(11):3719. 2. Daly JW, Adenosine receptors: development of selective agonists and antagonists. Prog Clin Biol Res. 1987;230:41-63. 3. Overington JP, et al. Nat Rev Drug Discov. 2006 Dec;5(12):1993-6.

Citations

1. Chen J, Li T, Huang D, et al.Integrating UHPLC-MS/MS quantitative analysis and exogenous purine supplementation to elucidate the antidepressant mechanism of Chaigui granules by regulating purine metabolism.Journal of Pharmaceutical Analysis.2023

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Tobacco Monomer Library Membrane Protein-targeted Compound Library Drug Repurposing Compound Library Human Endogenous Metabolite Library Microbial Natural Product Library Human Endogenous Metabolite Compound Library Plus Neuronal Signaling Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Xanthine 69-89-6 GPCR/G Protein Metabolism Neuroscience Adenosine Receptor Endogenous Metabolite inhibit Inhibitor 2,6-Dihydroxypurine Isoxanthine inhibitor

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